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Paper| Volume 28, ISSUE 3, P215-217, April 1997

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Possible implication of leukocytes in secondary pathological changes after spinal cord injury

  • S. Katoh
    Correspondence
    Requests for reprints should be addressed to: Mr S. Katoh, Department of Orthopedic Surgery, School of Medicine, The University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima 770, Japan.
    Affiliations
    Department of Orthopedic Surgery, School of Medicine, The University of Tokushima Tokushima, Japan

    The Midlands Centre for Spinal Injuries, the Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry, UK
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  • T. Ikata
    Affiliations
    Department of Orthopedic Surgery, School of Medicine, The University of Tokushima Tokushima, Japan
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  • M. Tsubo
    Affiliations
    Department of Orthopedic Surgery, School of Medicine, The University of Tokushima Tokushima, Japan

    The Midlands Centre for Spinal Injuries, the Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry, UK
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  • Y. Hamada
    Affiliations
    Department of Orthopedic Surgery, School of Medicine, The University of Tokushima Tokushima, Japan
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  • W.S. El Masry
    Affiliations
    The Midlands Centre for Spinal Injuries, the Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry, UK

    University of Keele, Keele, UK
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      Abstract

      We reviewed 95 consecutive patients with cervical spinal cord injury admitted within 2 days of injury and treated non-operatively, to elucidate the relationship between neurological deterioration and the white blood cell count in the first 4 days after injury. The count for 14 patients who had neurological deterioration was 13.2 ± 3.2 × 109/l, and that for 81 patients who had no deterioration was 11.0 ± 3.1 × 109/l. None of 19 patients whose highest white blood cell count was less than 9 × 109/l deteriorated, while 14 of 76 patients whose count was 9 × 109/l or more deteriovated. These results suggest that the white blood cell is important in the secondary pathological changes after mechanical injury to the spinal cord.
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