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Paper| Volume 28, ISSUE 3, P199-202, April 1997

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The development of the growth plate after birth: a study by osteocalcin immunocytochemistry

  • O.O.A. Oni
    Correspondence
    Requests for reprints should be addressed to: Mr O. O. A. Oni, The Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK.
    Affiliations
    The Glenfield Hospital, Groby Road, Leicester, UK
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      Abstract

      The post natal development of the growth plate was studied in the rabbit lower limb using an immunocytochemical technique which localized osteocalcin in situ. At birth, there is poor colummar organization of the physis and bone is not produced. Instead the predominant activity is cartilage remodelling. The columnar architecture develops later when endochondral ossification is also observed.
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