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The repair process using Phemister-Charnley bone-grafting in 3-week-old radial fractures
of dogs and the contribution of the graft to the process have been experimentally
studied. The dogs were sacrificed from 3 days to 12 weeks after bone-grafting; the
results were evaluated histologically, histochemically, by the oxytetracycline (OTC)
fluorescence method, and by microradiography. Marginally the graft was invaded at
an early stage by granulation tissue and new bone, mainly from the periosteum. The
trabeculae of the cancellous bone-graft preserved their osteocyte nuclei in places
for 4 weeks, although areas without nuclei were found. Six weeks after grafting, bony
union between the fragments was verified by all methods. Remodelling occurred in accordance
with the functional demand. In this study Phemister-Charnley bone-grafting seemed
to activate repair, particularly in the early stage.
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© 1971 Published by Elsevier Inc.