This paper is only available as a PDF. To read, Please Download here.
This study in 8 injured patients, 4 of whom were also paralysed showed that:—
- 1.Identical increased sedimentation rates, increased concentrations of α2 globulins, and increased rates of catabolism of albumin were observed in both the paralysed and non-paralysed patients following reparative surgery of a fractured tibia and fibula or extensive decubital ulcers.
- 2.Plasma albumin concentrations were subnormal in both groups of patients following the operations.
- 3.The paralysed patients showed an extravascular content of albumin which was about twice that found in normal individuals. The extravascular content of albumin in the non-paralysed injured patients was only slightly elevated above normal.
- 4.The limits of the rate of synthesis of albumin were subnormal in both the paralysed and non-paralysed patients except during a few days immediately after the operation.
- 5.The significance of these results in the absence of an intact nerve pathway from the site of injury is discussed.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to InjuryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Studies on Trauma. I. Intravascular Aggregation of Erythrocytes and Changes in Serum Proteins and Protein Bound Carbohydrates.Acta chir. scand. 1965; 130: 399
- Haemoglobin Metabolism and Serum Proteins following Trauma.Acta med. scand. 1956; 153: 319
- Studies on Burns. IX. The Distribution and Losses through the Wound of 131I Albumin measured by Whole Body Counting.Acta chir. scand. 1968; 134: 27
- Albumin Catabolism in Burns and following Surgical Procedures.Acta chir. scand. 1959; 118: 353
- Metabolism of 131I Labelled Human Albumin.Clin. Sci. 1961; 20: 161
- The Disturbance of Metabolism produced by Bony and Non Bony Injury with Notes on Certain Abnormal Conditions of Bone.Biochem. J. 1930; 24: 1244
- Protein Metabolism in Burned Patients treated in a Warm (32°C.) or Cool (22°C.) Environment.Injury. 1969; 1: 43
- Fibrinogen Metabolism following Injury and its Surgical Treatment.Injury. 1970; 1: 178
- Studies of Plasma Protein Metabolism. I. Albumin in Burned and Inuured Patients.Clin. Sci. 1962; 23: 411
- Studies of Plasma Protein Metabolism. II. Pooled γ Globulin in Burned and Injured Patients.Clin. Sci. 1963; 24: 371
- Pituitary Adrenal Response following Trauma to the Isolated Leg.Surgery, St Louis. 1959; 46: 9
- Pituitary Adrenal Activation following Different Types of Trauma.in: Combined Injuries and Shock: Intermedes Proceedings, 19671968: 91
- Studies on Burns. VII. The Problem of Infection with Special Reference to Gamma Globulin.Acta chir. scand. 1963; (Suppl.): 309
- Studies on Trauma. III. Plasma Iron Elimination Rate.Acta chir. scand. 1969; 135: 275
- Turnover of Human Serum Albumin before and after Operations.Clin. Sci. 1967; 33: 345
- Clinical Whole Body Counting—Whole Body Scanner with Two Crystals.Acta radiol. 1966; 4: 209
- Difference in Daily Albumin Synthesis between Normal Men and Women as measured with 131I Labelled Albumin.J. Lab. clin. Med. 1960; 55: 904
- Radioisotope Techniques in Clinical Research and Diagnosis.in: Butterworths, London1958: 324
Article info
Identification
Copyright
© 1970 Published by Elsevier Inc.
