Research Article| Volume 1, ISSUE 3, P235-239, January 1970

The error in predicting the normal blood-volume

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      Blood-volumes measured by Evans blue in 41 normal subjects are compared with those predicted for the same subjects from various formulae. The difference exceeds 500 ml. in 41 per cent of cases and 700 ml. in 20 per cent. Examples are quoted to show how even larger errors may arise in certain clinical situations. Attention is drawn to the fact that normal values predicted from certain formulae require correction if used with semi-automatic instruments which compute the blood-volume from the dilution of radioisotopes in whole blood without allowing for the body haematocrit/venous haematocrit ratio.
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