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Comment to: Frostbite of the extremities – recognition, evaluation and treatment

Frostbite and Botulinum Toxin A
  • Jean-Baptiste de Villeneuve Bargemon
    Correspondence
    Corresponding author at: 191 Boulevard Baille 13005, Marseille, France.
    Affiliations
    Hand Surgery and Limb Reconstructive Surgery Department, La Timone Adultes Hospital, Aix Marseille University, 264 rue Saint Pierre, 13005 Marseille, France

    International Wrist Center, Clinique Bizet, Paris, France
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  • Clément Prenaud
    Affiliations
    International Wrist Center, Clinique Bizet, Paris, France

    Department of Orthopaedic Surgery, Public Assistance Hospital of Paris, 125 Rue de Stalingrad, 93000 Bobigny
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Published:September 30, 2022DOI:https://doi.org/10.1016/j.injury.2022.09.060
      The authors of this work report a well-documented literature of frostbite management [
      • Persitz J.
      • Essa A.
      • Ner E.B.
      • Assaraf E.
      • Avisar E.
      Frostbite of the extremities – recognition.
      ]. Recently, another review of the literature has been published, confirming and reinforcing the claims of this study [
      • Sheridan R.L.
      • Goverman J.M.
      • Walker T.G.
      Diagnosis and treatment of frostbite.
      ]. As these publications describe it, the physiopathology of frostbite results from a cellular destruction release of vasoactive substances combined with thrombotic phenomena by crystallization of intracellular water. These phenomena can be immediate with the action of the gel but can also occur later, with ischemia-reperfusion phenomena, causing secondary and iterative amputations [
      • Sheridan R.L.
      • Goverman J.M.
      • Walker T.G.
      Diagnosis and treatment of frostbite.
      ,
      • Regli I.B.
      • Strapazzon G.
      • Falla M.
      • Oberhammer R.
      • Brugger H.
      Long-term sequelae of frostbite—a scoping review.
      ]. The use of vasodilators and antithrombotics therefore remain the cornerstone of the treatment. Regarding Botulinum Toxin, none of the published literature reviews consider its use in their therapeutic arsenal.

      Keywords

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        • Essa A.
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        Frostbite of the extremities – recognition.
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