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Novel approaches in biomaterial- and cell-based bone regeneration

      The aim of this special issue is to highlight recent advances in biomaterial- and cell-based bone regeneration for large-size defects, complex fractures and fractures at risk of infection. The special issue is introduced by two comprehensive reviews, with Ganguly et al. [
      • Ganguly P.
      • Jones E.
      • Panagiotopoulou V.
      • Jha A.
      • Blanchy M.
      • Antimisiaris S.
      • Anton M.
      • et al.
      Electrospun and 3D printed polymeric materials for one-stage critical-size long bone defect regeneration inspired by the Masquelet technique: Recent Advances.
      ] focussed on polymeric materials for critical-size long bone defect regeneration and Panagiotopoulou et al. [
      • Panagiotopoulou V.C.
      • Santolini E.
      • Jones E.
      • Jha A.
      • Giannoudis P.V.
      Adhesives for treatment of bone fractures: A review of the state-of-the art.
      ] - on bone adhesives. The use of bone adhesives is becoming promising, particularly for highly fragmented fractures, bone voids and for promoting osseointegration, and the review describes the essential properties of adhesives in fracture treatment. Regarding the polymeric materials, Gangluly et al. summarises recent advances in electrospining and 3D printing technologies, for the manufacture of membrane wraps for bone quided regeneration and whole implants, respectively.
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      References

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        Electrospun and 3D printed polymeric materials for one-stage critical-size long bone defect regeneration inspired by the Masquelet technique: Recent Advances.
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