- •Among road users with major trauma, those with higher Charlson Comorbidity Index score, cardiovascular diseases and diabetes were more likely to die, regardless of age and road user type. The association between death and cardiovascular diseases was stronger in males than females.
- •Pedestrians with severe injury (ISS ≥25) and severe impaired consciousness (GCS total score 3-8) were more likely to die, regardless of pre-existing comorbidities or age, compared to car occupants.
- •Our findings highlight the need to identify ways to enhance the management of road trauma patients with pre-existing cardiovascular diseases, diabetes, or multiple comorbidities, as well as the need to prioritize actions to prevent pedestrian crashes in strategies to reach Vision Zero.
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