Advertisement
Research Article| Volume 53, ISSUE 4, P1438-1442, April 2022

Predicting morbidity and mortality in Australian paediatric trauma with the Paediatric Age-Adjusted Shock Index and Glasgow Coma Scale

Published:January 20, 2022DOI:https://doi.org/10.1016/j.injury.2022.01.034

      Highlights

      • We evaluate the Pediatric age-adjusted shock index (SIPA) for the first time in Australia
      • The First SIPA study to include pediatric trauma patients of all severity and ages shows that it loses correlation in the generalised population
      • SIPA in combination with GCS (SIPAms) on arrival predicts morbidity outcomes more strongly than pre-arrival, but both predict more outcomes than SIPA without GCS.
      • SIPAms increases sensitivity significantly for predictors of morbidity with a mild loss of specificity. aSIPAms has a sensitivity of 76% and specificity of 70% for major trauma.

      Abstract

      Background

      Paediatric age-adjusted shock index (SIPA) has emerged as a predictor of morbidity and mortality in trauma. Poor sensitivity and low generalisability demonstrated in previous studies have limited its use. We evaluate the use of SIPA in the general Australian paediatric trauma population and the combination of SIPA with GCS.

      Methods

      All patients from January 2015 to August 2020 at a major Australian paediatric trauma centre were reviewed. Pre-arrival SIPA (pSIPA) and arrival SIPA (aSIPA) were calculated. If SIPA was elevated or the Glasgow Coma Scale ≤ 13, SIPA with mental state (SIPAms) was marked positive for pre-arrival (pSIPAms) and arrival (aSIPAms) respectively.

      Results/Discussion

      Data from 480 patients were analysed. pSIPA and aSIPA poorly predicted outcomes of morbidity. Only aSIPA predicted mortality. However, both pre-arrival and arrival SIPAms variables predict mortality, major trauma (ISS≥12), hospital LOS, need for ICU admission, and major surgery. Furthermore, median ISS and lactate were significantly higher in positive pSIPA, aSIPA, pSIPAms, and aSIPAms groups than negative. aSIPAms has a sensitivity of 76% and specificity of 70% for major trauma.

      Conclusion

      Broad inclusion criteria reduce SIPA's ability to predict morbidity. Combining it with GCS improves this and is most valuable when calculated at arrival. In addition, the score is more reliable for major trauma (ISS≥12). Future studies should evaluate the use of SIPAms in activation criteria.

      Keywords

      Abbreviations:

      aSIPA (Shock Index, Pediatric age-adjusted, calculated on arrival), aSIPAms (Shock Index, Pediatric age-adjusted, with mental state, calculated on arrival), GCS (Glasgow Coma Scale), GCS-M (Motor component of Glasgow Coma Scale), HR (Heart Rate), ICU (Intensive Care Unit), ISS (Injury Severity Score), LOS (Length of Stay), pSIPA (Shock Index, Pediatric age-adjusted, calculated pre-arrival), pSIPAms (Shock Index, Pediatric age-adjusted, with mental state, calculated pre-arrival), SBP (Systolic Blood Pressure), SI (Shock Index), SIPA (Shock Index, Pediatric age-adjusted), SIPAms (Shock Index, Pediatric age-adjusted, with mental state)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Injury
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Singh A
        • Ali S
        • Agarwal A
        • Srivastava RN.
        Correlation of shock index and modified shock index with the outcome of adult trauma patients: a prospective study of 9860 patients.
        North American J Med Sci. 2014; 6: 450-452
        • Montoya KF
        • Charry JD
        • Calle-Toro JS
        • Núñez LR
        • Poveda G
        Shock index as a mortality predictor in patients with acute polytrauma.
        J Acute Dis. 2015; 4: 202-204
        • Acker SN
        • Ross JT
        • Partrick DA
        • Tong S
        • Bensard DD.
        Pediatric specific shock index accurately identifies severely injured children.
        J Pediatr Surg. 2015; 50: 331-334
        • Linnaus ME
        • Notrica DM
        • Langlais CS
        • St. Peter SD
        • Leys CM
        • Ostlie DJ
        • et al.
        Prospective validation of the shock index pediatric-adjusted (SIPA) in blunt liver and spleen trauma: An ATOMAC+ study.
        J Pediatr Surg. 2017; 52: 340-344
        • Acker SN
        • Bredbeck B
        • Partrick DA
        • Kulungowski AM
        • Barnett CC
        • Bensard DD.
        Shock index, pediatric age-adjusted (SIPA) is more accurate than age-adjusted hypotension for trauma team activation.
        Surgery. 2017; 161: 803-807
        • Acker S
        • Ross J
        • Partrick D
        • Bensard D.
        A pediatric specific shock index in combination with GMS identifies children with life threatening or severe traumatic brain injury.
        Pediatr Surg Int. 2015; 31: 1041-1046
        • Nordin A
        • Coleman A
        • Shi J
        • Wheeler K
        • Xiang H
        • Acker S
        • et al.
        Validation of the age-adjusted shock index using pediatric trauma quality improvement program data.
        J Pediatr Surg. 2018; 53: 130-135
        • Vandewalle RJ
        • Peceny JK
        • Dolejs SC
        • Raymond JL
        • Rouse TM.
        Trends in pediatric adjusted shock index predict morbidity and mortality in children with severe blunt injuries.
        J Pediatr Surg. 2018; 53: 362-366
        • Nordin A
        • Shi J
        • Wheeler K
        • Xiang H
        • Kenney B.
        Age-adjusted shock index: From injury to arrival.
        J Pediatr Surg. 2019; 54: 984-988
        • Cotton BA
        • Nance ML.
        Penetrating trauma in children.
        Semin Pediatr Surg. 2004; 13: 87-97
        • Coulthard MG
        • Varghese V
        • Harvey LP
        • Gillen TC
        • Kimble RM
        • Ware RS.
        A review of children with severe trauma admitted to pediatric intensive care in Queensland.
        Australia. PloS one. 2019; 14 (-e)e0211530
        • Welfare AIoHa
        Australia's children.
        CWS 69 ed. AIHW, Canberra2020
        • Gandhi G
        • Claiborne MK
        • Gross T
        • Sussman B
        • Davenport K
        • Bulloch B.
        Comparison of prehospital calculated age-adjusted pediatric shock index (SIPA) to those calculated in the ED for identifying trauma patients that needed the highest-level activation based on consensus criteria.
        Prehospital Emerg Care. 2020; (ahead-of-print(ahead-of-print)): 1
        • Gandhi G
        • Claiborne MK
        • Gross T
        • Sussman BL
        • Davenport K
        • Ostlie D
        • et al.
        Predictive value of the shock index (SI) compared to the age-adjusted pediatric shock index (SIPA) for identifying children that needed the highest-level trauma activation based on the presence of consensus criteria.
        J Pediatr Surg. 2019;
        • Drendel AL
        • Gray MP
        • Lerner EB.
        A systematic review of hospital trauma team activation criteria for children.
        Pediatr Emerg Care. 2019; 35: 8-15
        • Van Ditshuizen JC
        • Sewalt CA
        • Palmer CS
        • Van Lieshout EMM
        • Verhofstad MHJ
        • Den Hartog D
        The definition of major trauma using different revisions of the abbreviated injury scale.
        Scandinavian J Trauma, Resusc Emerg Med. 2021; 29: 71
        • Vandewalle R
        • Peceny J
        • Raymond J
        • Rouse T
        Trends in pediatric-adjusted shock index predict morbidity in children with moderate blunt injuries.
        Pediatr Surg Int. 2019; 35: 785-791
        • Notrica DM
        • rJW Eubanks
        • Tuggle DW
        • Maxson RT
        • Letton RW
        • Garcia NM
        • et al.
        Nonoperative management of blunt liver and spleen injury in children: evaluation of the ATOMAC guideline using GRADE.
        J Trauma Acute Care Surg. 2015; 79: 683-693
        • Djordjevic I
        • Slavkovic A
        • Marjanovic Z
        • Zivanovic D.
        Blunt trauma in paediatric patients - experience from a small centre.
        West Indian Med J. 2015; 64: 126-130
        • Shah A
        • Guyette F
        • Suffoletto B
        • Schultz B
        • Quintero J
        • Predis E
        • et al.
        Diagnostic accuracy of a single point-of-care prehospital serum lactate for predicting outcomes in pediatric trauma patients.
        Pediatr Emerg Care. 2013; 29: 715-719
        • Lee E-P
        • Chu S-C
        • Hsia S-H
        • Chen K-F
        • Chan O-W
        • Lin C-Y
        • et al.
        Comparison of predictive powers for mortality between systemic vascular resistance index and serum lactate in children with persistent catecholamine-resistant shock.
        Biomed Res Int. 2020; 2020: 1-10
        • Phillips R
        • Acker S
        • Shahi N
        • Shirek G
        • Meier M
        • Goldsmith A
        • et al.
        The shock index, pediatric age-adjusted (SIPA) enhanced: Prehospital and emergency department SIPA values forecast transfusion needs for blunt solid organ injured children.
        Surgery. 2020; 168: 690-694
        • Traynor MD
        • St. Louis E
        • Hernandez MC
        • Alsayed AS
        • Klinkner DB
        • Baird R
        • et al.
        Comparison of the pediatric resuscitation and trauma outcome (PRESTO) model and pediatric trauma scoring systems in a middle-income country.
        World J Surg. 2020; 44: 2518-2525