Advertisement
Research Article| Volume 50, SUPPLEMENT 5, S64-S67, December 2019

Management of large peripheral nerve defects with autografting

Published:October 21, 2019DOI:https://doi.org/10.1016/j.injury.2019.10.051

      Abstract

      Introduction

      A segmental nerve defect from trauma results in significant loss of function of the extremity, and rarely occurs in isolation. Autografting of the nerve defect is the current gold standard.

      Methods

      A review of the recent literature regarding peripheral nerve defects after trauma treated with autograft.

      Results

      Identification of the zone of nerve injury is difficult and appropriate resection is critical for good outcomes. Meaningful recovery is more likely with application of excellent technique. Many of the factors affecting outcomes are not modifiable.

      Conclusion

      Nerve grafting for segmental nerve injuries continues to be an essential and appropriate treatment.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Injury
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Boyd K.U.
        • Nimigan A.S.
        • Mackinnon S.E.
        Nerve reconstruction in the hand and upper extremity.
        Clin Plast Surg. 2011; 38: 643-660
        • Isaacs J.
        • Safa B.
        A preliminary assessment of the utility of large-caliber processed nerve allografts for the repair of upper extremity nerve injuries.
        Hand. 2017; 12: 55-59
        • Forli A
        • Bouyer M
        • Aribert M
        • Curvale C
        • Delord M
        • Corcella D
        • et al.
        Upper limb nerve transfers: a review.
        Hand Surg Rehabil. 2017; 36: 151-172https://doi.org/10.1016/j.hansur.2016.11.007
        • Berger A
        • Millesi H
        Nerve grafting.
        Clin Orthop Relat Res. 1978; 133: 49-55
        • Moore A.
        • Wagner I.
        • Fox I.
        Principles of nerve repair in complex wounds of the upper extremity.
        Semin Plast Surg. 2015; 29: 40-47
        • Kalomiri D.E.
        • Soucacos P.N.
        • Beris AE
        Nerve grafting in peripheral nerve microsurgery of the upper extremity.
        Microsurgery. 1994; 15: 506-511
        • Rbia N.
        • Shin A.Y.
        The role of nerve graft substitutes in motor and mixed motor/sensory peripheral nerve injuries.
        J Hand Surg Am. 2017; 42: 367-377
        • Wang E.M.
        • Inaba K.M.
        • Byerly S.M.
        • Escamilla D.
        • Cho J.M.
        • Carey J.M.
        • et al.
        Optimal timing for repair of peripheral nerve injuries.
        J Trauma Acute Care Surg. 2017; 83: 875-881
        • Trehan S.K.
        • Model Z.
        • Lee S.K.
        Nerve repair and nerve grafting.
        Hand Clin. 2016; 32: 119-125
        • Birch R.
        • Raji A.R.
        Repair of median and ulnar nerves. primary suture is best.
        J Bone Jt Surg Br. 1991; 73: 154-157
        • Fu S.Y.
        • Gordon T.
        Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation.
        J Neurosci. 1995; 15: 3886-3895
        • Kallio P.K.
        • Vastamäki M.
        • Solonen K.A.
        The results of secondary microsurgical repair of radial nerve in 33 patients.
        J Hand Surg. 1993; 18 ((British Eur Vol): 320-322
        • Vastamäki M.
        • Kallio P.K.
        • Solonen K.A.
        The results of secondary microsurgical repair of ulnar nerve injury.
        J Hand Surg. 1993; 18 ((British Eur Vol): 323-326
        • Kallio P.K.
        • Vastamäki M.
        An analysis of the results of late reconstruction of 132 median nerves.
        J Hand Surg Am. 1993; 18: 97-105
        • Jaquet J-B
        • Luijsterburg AJ
        • Kalmijn S
        • Kuypers PDL
        • Hofman A
        • Hovius SER
        Median, ulnar, and combined median-ulnar nerve injuries: functional outcome and return to productivity.
        J Trauma Inj Infect Crit Care. 2001; 51: 687-692
        • Grinsell D.
        • Keating C.P.
        Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies.
        Biomed Res Int. 2014; 2014698256