Advertisement
Research Article| Volume 43, ISSUE 10, P1698-1703, October 2012

Download started.

Ok

Early or delayed operation, which is more optimal for kyphoplasty? A retrospective study on cement leakage during kyphoplasty

      Abstract

      Purpose

      To retrospectively assess the optimal operating time for kyphoplasty as far as the cement leakage during kyphoplasty is concerned.

      Materials and methods

      One hundred and six patients with a total of 117 osteoporotic vertebral compression fractures (VCFs) were enrolled in our study. According to the time of kyphoplasty, they were divided into two groups: group 1 (early operation group, who received the operation within 14 days after fracture, n = 46) and group 2 (delayed operation group, who received the operation between 15 and 28 days after fracture, n = 71). Preoperative and postoperative visual analogue scale (VAS) and Oswestry Disability Index (ODI) scores were compared 3 days after surgery within each group and between the two groups. The radiographic outcomes were evaluated by the restoration rate (RR) of the treated vertebrae. The outcome of cement leakage was assessed after surgery using X-ray and computed tomography (CT) scans. Leaks of cement were classified into three types: those via the basivertebral vein (type B), via the segmental vein (type S) and through a cortical defect (type C).

      Results

      The mean VAS and ODI scores decreased significantly from pre-surgery to post-surgery in each group, as did the RR (p > 0.05). There was no significant difference postoperatively on VAS and ODI scores (p > 0.05) between the two groups. However, significant differences were observed postoperatively on RR (p = 0.045) and vertebrae with leakage (p = 0.038). In addition, there was a significant difference on leakage site of type C between the two groups (p = 0.032).

      Conclusion

      Both early and delayed operations of kyphoplasty can achieve satisfactory clinical and radiographic outcomes for osteoporotic VCFs. The risk of cement leakage during kyphoplasty will decrease obviously in delayed operation; so delayed operation, perhaps 2 weeks after fracture, is more safe and optimal than early operation as far as cement leakage is concerned, especially for vertebrae with cortical defects. But early operation of kyphoplasty is more effective in vertebral height restoration.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Injury
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Taylor R.S.
        • Fritzell P.
        • Taylor R.J.
        Balloon kyphoplasty in the management of analysis.
        European Spine Journal. 2007; 16: 1085-1100
        • Garfin S.R.
        • Yuan H.A.
        • Reiley M.A.
        New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures.
        Spine. 2001; 26: 1511-1515
        • Harrinton K.D.
        Major neurological complications following percutaneous vertebroplasty with polymethylmethacrylate.
        Journal of Bone and Joint Surgery. 2001; 83: 1070-1073
        • Lin E.P.
        • Ekholm S.
        • Hiwatashi A.
        • et al.
        Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body.
        American Journal of Neuroradiology. 2004; 25: 175-180
        • Luo J.
        • Skrzypiec D.M.
        • Pollintine P.
        • Adams M.A.
        • Annesley-Williams D.J.
        • Dolan P.
        Mechanical efficacy of vertebroplasty: influence of cement type, BMD, fracture severity, and disc degeneration.
        Bone. 2007; 40: 1110-1119
        • Yeom J.S.
        • Kim W.J.
        • Choy W.S.
        • et al.
        Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fractures.
        Journal of Bone and Joint Surgery British Volume. 2003; 85: 83-89
        • Phillips F.M.
        • Todd W.F.
        • Lieberman I.
        • et al.
        An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty.
        Spine. 2002; 27: 173-178
        • Vasconcelos C.
        • Gailloud P.
        • Martin J.B.
        • et al.
        Transient arterial hypotension induced by polymethylmethacrylate injection during percutaneous vertebroplasty.
        Journal of Vascular and Interventional Radiology. 2001; 12: 1001-1002
        • Lin E.P.
        • Ekholm S.
        • Hiwatashi A.
        • et al.
        Vertebroplasty: cement leakage into the disc increased the risk of new fracture of adjacent vertebral body.
        American Journal of Neuroradiology. 2004; 25: 175-180
        • Jiahau Y.
        • John M.
        • Kari C.
        How tough is bone? Application of elastic–plastic fracture mechanics to bone.
        Bone. 2007; 40: 479-484
        • Lee B.J.
        • Lee S.R.
        • Yoo T.W.
        Paraplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate: a case report.
        Spine. 2002; 27: 419-422
        • Reinhard G.
        • Hannjorg K.
        • Bruce D.
        Fracture healing in the elderly patient.
        Experimental Gerontology. 2006; 41: 1080-1093
        • Atsushi K.
        • Noboru T.
        • Shuji K.
        • et al.
        Percutaneous vertebroplasty for osteoporotic compression fracture: multivariate study of predictors of new vertebral body fracture.
        Cardiovascular and Interventional Radiology. 2006; 29: 580-585
        • Kaufmann T.J.
        • Trout A.T.
        • Kallmes D.F.
        The effects of cement volume on clinical outcomes of percutaneous vertebroplasty.
        American Journal of Neuroradiology. 2006; 27: 1933-1937
        • Uthoff H.K.
        • Jaworski Z.F.
        Bone loss in response to long term immobilization.
        Journal of Bone and Joint Surgery British Volume. 1978; 60: 420-429