Abstract
We studied if a static or dynamic mode of nail fixation influenced the healing of
segmental defect reconstructions in long bones. Defects in the femur of goats were
reconstructed using a cage filled with firmly impacted morsellised allograft mixed
with a hydroxyapatite paste (Ostim). All reconstructions were stabilised with an intramedullary
nail. In one group (n = 6) the intramedullary nail was statically locked, in the second group (n = 6) a dynamic mode of nail fixation was applied. We hypothesised that dynamisation
of the nail would load, and by that stimulate the healing of the bone graft. Mechanical
torsion strength of the reconstructions of the femur with the static and dynamic mode
of nail fixation appeared to be 74.8 ± 17.5% and 73.0 ± 13.4%, respectively as compared with the contralateral femurs after 6 months. In all
reconstructions, the grafts united radiographically and histologically to the host
bone, and remodelled into a new vital bone structure. No large differences were found
between newly formed bone areas inside and outside the mesh of the two groups. The
area of callus outside the mesh in the dynamic mode of fixation group was smaller
(p = 0.042), whilst the percentage of bone outside the mesh was larger (p = 0.049), as compared to the static mode of fixation group. The data suggest that healing
of these defects with impacted morsellised graft in a cage is not significantly influenced
by the mode of fixation of the nail in this model.
Keywords
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Article info
Publication history
Accepted:
July 12,
2010
Identification
Copyright
© 2010 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
