Abstract
Using an experimental model of segmental bone defect in the ulna of rabbits we investigated
the effect on bone healing of fresh cancellous autograft (FCA), demineralized deep-frozen
allograft (DDA), and demineralized deep-frozen allograft covered with free autogenous
periosteum (DDAwP).
Radiologically, it was found that the results of the FCA and DDAwP groups were superior
to those of the DDA group. This superiority was statistically significant after the
3rd to the 9th week for the FCA group, and the 6th to the 9th week for the DDAwP group.
However, bone formation and union in the DDA group reached the same level of those
in the other groups after 12 weeks. When the all histological findings were compared
at the 12th week, the FCA and DDAwP groups were statistically superior to the DDA
group in terms of proximal union. On distal union, the FCA group was statistically
superior to the DDA group. Biomechanically, the FCA and DDAwP groups were statistically
superior to the DDA group in terms of maximum torque and energy absorption. The DDAwP
group was superior to the DDA group in term of stiffness. We conclude that ossification
could be more easily achieved if demineralized deep-frozen allograft is covered with
periosteum when faced with the need for quicker and better quality bone integration.
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Article info
Publication history
Accepted:
January 15,
2002
Identification
Copyright
© 2002 Elsevier Science Ltd. Published by Elsevier Inc. All rights reserved.
