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Research Article| Volume 31, SUPPLEMENT 4, D37-D47, December 2000

Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements

DOI:https://doi.org/10.1016/S0020-1383(00)80022-4
Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements
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      Abstract

      Calcium phosphate (CaP) compounds are becoming of increasingly great importance in the fiel of biomaterials and, in particular, as bone substitutes. Recent discoveries have accelerated this process, but have simultaneously rendered the field more complicated for the everyday user. Subtle differences in composition and structure of CaP compounds may have a profound effect on their in vivo behaviour. Therefore, the main goal of this article is to provide a simple, but comprehensive presentation of CaP compounds. Reference is made to the most important commercial products.

      Zusammenfassung

      Calciumphosphatverbindungen (CaP-Verbindungen) werden im Anwendungsgebiet von Biomaterialien und speziell als Knochenersatzmaterialien zunehmend wichtig. Neuere Erkenntnisse haben dazu beschleunigend beigetragen, gleichzeitig aber die Verständlichkeit der fachlichen Aspekte für den Nichtexperten wesentlich erschwert. Kleinste Unterschiede in der Zusammensetzung oder Struktur dieser CaP-Verbindungen können ihr in vivo Verhalten entscheidend beeinflussen. Das Hauptziel des vorliegenden Artikels ist deshalb, eine einfache aber dennoch umfassende Darstellung der CaP-Verbindungen zu vermitteln. Zudem wird eine Reihe von Hinweisen betreffend der wichtigsten kommerziellen. Produkte gegeben.

      Résumé

      Les composés phosphocalciques sont utilisés de plus en plus dans le domaine des biomatériaux, particulièrement comme os de substitution. Cette tendance s'est accentuée avec des découvertes récentes, de telle sorte que le domaine des ciments est devenu particulièrement complexe pour l'usager. Des différences subtiles de composition et de structure des composés phosphocalciques peuvent avoir un effect considérable sur leur comportement in vivo. L'objectif de cet article est de présenter une mise au point claire et simple de l'ensemble des composés phosphocalciques. La discussion porte sur les principaux produits commerciaux.

      Resumen

      Los compuestos de fosfato de calcio (CaP) están cobrando cada vez más importancia en el campo de los biomateriales y, en particular, como sustitutos óseos. Recientes descubrimientnos han acelerado este proceso, pero a la vez han complicado este campo para la rutina diaria de sus usuarios. Sutiles diferencias de composición y estructura de los compuestos de CaP pueden tener un profundo efecto sobre su comportamiento in vivo. El principal objetivo de este artículo es, pues, ofrecer una presentación sencilla pero exhaustiva de los compuestos de CaP. Se hace referencia a los productos comerciales más importantes.

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      DOI: https://doi.org/10.1016/S0020-1383(00)80022-4

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      © 2000 Published by Elsevier Inc.

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