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Abstract
Ten cases of experimental atrial rupture were created in five pigs by cutting into
both atria. The defects measured approximately 3.0 × 1.0 cm. Bleeding was stopped
by applying a tangential clamp and the defect in the atrium was sealed with fibrin
glue (mean volume 2.0 ml, range 1.5–2.5 ml) with a mean fibrin concentration of 23
mg/ml. The mean pressures in the atria were 11 cmH2O in the left and 10 cmH2O in the right atrium. The clamp was released after 5 min and the atria were observed
for bleeding for 30 min. In four animals, immediate haemostasis was obtained. In one
animal, both atria leaked after release of the clamp because too little fibrin glue
was applied, but complete haemostasis was obtained at a second attempt. All experimental
atrial defects could be sealed with fibrin glue (P = 0.03), and we believe, based on our experimental results, that fibrin glue may
have a place in emergency cases to improve the management of atrial injury. In conclusion
successful repair of experimental atrial rupture was performed by the use of fibrin
glue.
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Article info
Publication history
Accepted:
September 9,
1994
Identification
Copyright
© 1995 Published by Elsevier Inc.
