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Abstract
A randomized double-blind study was undertaken to investigate whether 0.25 per cent
bupivacaine administered intrapleurally is an effective and reasonably safe method
of obtaining analgesia in patients with thoracic injuries, A total of 120 patients
complaining of pain after chest injury were entered into the trial All had thoracostomy
tubes already in situ. Of 60 patients who were given the test dose of bupivacaine intrapleurally, 37 obtained
satisfactory pain relief for 2 or more hours compared with only 9 of 60 patients who
received saline P < 0.000001). Duration of analgesia in the test group (mean 3.9 h) was significantly
longer than that in the control group (mean 0.9 h) P < 0.005). There were no important side-effects attributable to the bupivacaine administered.
We conclude that intrapleural bupivacaine is an effective and reasonably safe method
for obtaining analgesia in patients who have chest drain tubes inserted.
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References
- Intrapleural administration of local anesthetics for pain relief in patients with multiple rib fractures.Reg. Anaesth. 1987; 12: 10
- Continuous intrapleural infusion of bupivacaine for analgesia after thoracotomy.Anesthesiology. 1987; 67: 811
- Intrapleural bupivacaine — a kinetic and dynamic evaluation.Anesthesiology. 1987; 67: 798
- Intrapleural administration of 0.25%, 0.375%, and 0.5% bupivacaine with epinephrine after cholecystectomy.Anesth. Analg. 1988; 67: 430
Article info
Publication history
Accepted:
June 11,
1990
Identification
Copyright
© 1991 Published by Elsevier Inc.
