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A series of 54 patients who had low-energy, closed fractures requiring internal fixation were entered into a randomized prospective study comparing prophylactic antibiotics with no treatment.
In five patients who did not have antibiotics a superficial wound infection or fever was recorded. In those who received antibiotics, no infection or fever was detected.
However, there was no statistical difference between the two groups, and it is concluded that there is no need for prophylactic antibiotics when internally fixing low-energy fractures.
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- Nonparametric Statistical Methods. Wiley, Chichester, UK1973
- Prophylactic cefuroxime in total joint replacement.Int. Orthop. 1982; 6: 155
- Penetration of antibiotics into bone.J. Antimicrob. Chemother. 1985; 15: 517
- The role of antibiotics in the management of open fractures.J. Bone Joint Surg. 1974; 56A: 532
- The volume of distribution of ceftazidime and albumin in normal, immature and infected bone.J. Antimicrob. Chemother. 1986; 18: 381
- Infection prophylaxis in orthopaedic surgery.in: Res. Clin. Forums. 5. 1983: 37
- Multivariate analysis of determinants of postoperative wound infection in orthopaedic patients.J. Hosp. Infect. 1984; 5: 137
Accepted: June 15, 1990
© 1991 Published by Elsevier Inc.