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Research Article| Volume 18, ISSUE 5, P327-328, September 1987

CSF rhinorrhoea: significance of the glucose oxidase strip test

  • D.J. Steedman
    Correspondence
    Requests for reprints should be addressed to: D. J. Steedman, Senior Registrar, Department of Accident and Emergency Medicine, Royal Infirmary, Lauriston Place, Edinburgh EH3 9YW.
    Affiliations
    Department of Accident and Emergency Medicine, Royal Infirmary, Edinburgh UK
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  • M. Gordon
    Affiliations
    Department of Accident and Emergency Medicine, Royal Infirmary, Edinburgh UK
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      Abstract

      Many authoritative medical textbooks recommend the use of glucose oxidase reagent strips to distinguish cerebrospinal fluid rhinorrhoea from clear nasal discharge following head injury. A study of 50 subjects with clear nasal and lacrimal secretions, demonstrated a large proportion of positive results for glucose (44 per cent). Thirteen secretions (26 per cent) contained glucose in a concentration within the normal range for CSF. The recommended use of glucose oxidase test strips for differentiating CSF leakage from other clear nasal secretions is therefore without foundation.
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