This paper is only available as a PDF. To read, Please Download here.
The purpose of the present study was to investigate the effect of simulated joint effusion on po2, pco2, the regional blood flow and intraosseous bone marrow pressure in the subchondral bone of rabbit.
Mass spectrometry was used for simultaneous and continuous registration of subchondral po2 and pco2, while the relative argon signal was used for qualitative estimation of regional bone blood flow. The bone marrow pressure was recorded continuously by pressure transducers. Isotonic sodium chloride infusion at a constant pressure of 75 mmHg into the knee joint cavity constituted the basis for joint effusion.
An instant increase in the subchondral bone marrow pressure followed the joint effusion (P < 0.001). This resulted in a significant (P < 0.01) decrease in the qualitative bone blood flow, significant (P < 0.01) hypoxia and significant (P < 0.01) hypercapnia in the subchondral bone. Joint effusion always lasted 30 minutes. Following its release all changes were reversed to normal values within 15 minutes. Within the period of observation no nervous or humoral factors seem to be brought into action. It was concluded that regional venous stasis was responsible for all changes, and that joint effusion should not be left untreated for long periods.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Injury
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- The pathomechanism of human coxarthrosis.Acta Orthop. Scand. 1979; 181 (Suppl.)
- Skeletal and soft tissue changes in the lower leg in patients with intracalcanean hypertension.Acta Chir. Scand. 1972; 138: 25
- The effect of increased intraarticular pressure on juxta-articular bone marrow pressure.IRCS Med. Sci. 1979; 7: 471
- The effect of joint position on juxtaarticular bone marrow pressure.Acta Orthop. Scand. 1980; 51: 893
- A new concept of capillary circulation in the bone cortex.Lancet. 1961; i: 1078
- Intraosseous pressure in the knee in relation to simulated joint effusion, joint position and venous obstruction.Scand. J. Rheumatol. 1981; 10: 283
- Hemodynamics of the juvenile knee in relation to increasing intraarticular pressure.Acta Orthop. Scand. 1983; 54: 80
- The effect of joint position on pressure of intraarticular effusion.J. Bone Joint Surg. 1964; 46A: 1235
- Intraartikuläre Druchhöhung und epiphysäre Durchblutungsstörung. Ein experimentelles Untersuchungsmodell.Orthopäde. 1981; 10: 6
- Effect of increased knee joint pressure on oxygen tension and blood flow in subchondral bone.Acta Physiol. Scand. 1984; 121: 127
- Continuous measurement of subchondral pO2 and pCO2 by mass spectrometry.IRCS Med. Sci. 1983; 11: 583
- Hemodynamics of the femoral head.J. Bone Joint Surg. 1981; 63A: 442
- The relationship between increasing intraarticular pressure and intraosseous pressure in the juxtaarticular bones.Acta Orthop. Scand. 1981; 52: 491
- Blood flow in the juvenile hip in relation to changes of the intra-articular pressure.Acta Orthop. Scand. 1983; 54: 182
- Fast responding flow independent blood gas catheters for oxygen measurement.J. Appl. Physiol. 1980; 48: 376
- Dynamic influences of vascular occlusion affecting the development of vascular necrosis of the femoral head.Clin. Orthop. 1964; 32: 119
Accepted: July 24, 1985
© 1986 Published by Elsevier Inc.