Injury
Volume 38, Issue 1 , Pages 53-59 , January 2007

Effect of NO donor sodium nitroprusside on lipopolysaccharide induced acute lung injury in rats

  • Zhong-yuan Xia

      Affiliations

    • Anesthesiology Research Laboratory, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China
    • ,
  • Xiao-yuan Wang

      Affiliations

    • Anesthesiology Research Laboratory, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China
    • ,
  • Xiangdong Chen

      Affiliations

    • Anesthesiology Research Laboratory, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China
    • Department of Pharmacology, University of Virginia, Charlottesville, VA 22904, USA
    • Corresponding Author InformationCorresponding author at: Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China. Tel.: +86 27 88041919x2272; fax: +86 27 88042292.
    • ,
  • Zhengyuan Xia

      Affiliations

    • Anesthesiology Research Laboratory, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China
    • Centre for Anesthesia and Analgesia, Department of Pharmacology and Therapeutics, the University of British Columbia,Vancouver, Canada V6T 1Z3

,Accepted 27 September 2006.

References 

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  14. Otterbein LE, Bach FH, Alam J, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000;6:422–442
  15. Sarady JK, Zuckerbraun BS, Bilban M, et al. Carbon monoxide protection against endotoxic shock in involves reciprocal effects on iNOS in the lung and liver. FASEB J. 2004;18:854–856
  16. Schutte H, Lockinger A, Seeger W, Grimminger F. Aerosolized PGE1, PGI2 and nitroprusside protect against vascular leakage in lung ischaemia-reperfusion. Eur Respir J. 2001;18:15–22
  17. Slebos DJ, Rvter SW, Choie AM. Haeme oxygenase-1 and carbon monoxide in pulmonary medicine. Respir Res. 2003;4:7
  18. Sookhai S, Wang JJ, McCourt M, et al. A novel therapeutic strategy for attenuating neutrophil-mediated lung injury in vivo. Ann Surg. 2002;235:285–291
  19. Tavaf-Motamen H, Miner TJ, Starnes BW, Shea-Donohue T. Nitric oxide mediates acute lung injury by modulation of inflammation. J Surg Res. 1998;78:137–142
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PII: S0020-1383(06)00595-X

doi: 10.1016/j.injury.2006.09.021

Injury
Volume 38, Issue 1 , Pages 53-59 , January 2007

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